San Francisco start-up Seesmic laid off 18 employees this week, bringing its staff down to 15 people.
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When reached by phone today, CEO Loic Le Meur said the layoffs were only the latest size reduction Seesmic has seen, as it has reshaped itself many times. Since it launched in 2007, Seesmic has been a video platform, then made Twitter clients and other social tools, and last year tried to make a go with Salesforce CRM products.
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“What we’ve been trying for a long time has not worked the way we hoped,” Le Meur said.
In February, the company announced it would be changing and expanding the free Ping.fm social media cross-posting tools it bought in 2010 into a paid service called “Seesmic Ping.”

http://allthingsd.com/20120322/seesmic-lays-off-half-its-staff-as-it-pivots-back-to-social-cross-posting/?mod=atdtweet

Announcements of this kind are bound to become more and more frequent with the incoming implosion of tech bubble 2.0.
Seesmic looks very representative of this "launch a start-up, raise funds, then do the market study, and much later, think about how to make money" approach, which already lead to tech disaster 1.0.